David R. Murdock, M.D., F.A.C.M.G.

Assistant Professor
Baylor College of Medicine

David R. Murdock, M.D., F.A.C.M.G. Photo

Position

Address

Adult Genetics Clinic (Clinic)
Baylor College of Medicine Medical Center - McNair Campus
7200 Cambridge St.
9th Floor, Suite 9A
Houston, Texas 77030
United States
(713) 798-7764
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Certifications

  • Internal Medicine
    American Board of Internal Medicine

  • Clinical Genetics
    American Board of Medical Genetics and Genomics

  • Molecular Genetics
    American Board of Medical Genetics and Genomics

Education

  • BS from Rice University
    Houston, Texas United States

  • MD from Baylor College of Medicine
    Houston, Texas United States
  • Postdoctoral Fellowship at Baylor College of Medicine
    Houston, Texas United States

  • Residency at Louisiana State University Health Sciences Center
    Shreveport, Louisiana United States

  • Clinical Fellowship at the National Institutes of Health
    Bethesda, Maryland United States

  • Fellowship at the National Institutes of Health
    Bethesda, Maryland United States

Professional Statement

My clinical and research interests involve connective tissue disorders such as Marfan syndrome and Loeys-Dietz syndrome, conditions that lead to aortic aneurysms and dissections. I am particularly interested in identifying new genes associated with such aortopathies and exploring the mechanisms of genetically-mediated aneurysm development. I also study Xia-Gibbs syndrome, a developmental disorder due to truncating mutations in the AHDC1 gene. The goal of these research efforts is to develop new therapies to improve outcomes. Among the tools I use are whole exome and genome sequencing as well as RNAseq. As a member of the adult genetics team I diagnose and manage adults with a variety of genetic conditions (e.g., cancer). I am also the assistant director of the HGSC CAP/CLIA clinical lab where I perform analysis, interpretation, and reporting of sequencing data. I am committed to the growing field of personalized medicine through the eMERGE and BCM Cardiovascular Disease Genetics efforts. Lastly, I am dedicated to education and enjoy teaching about principles of genetics.

Professional Interests

  • Connective Tissue Disorders (Marfan, Loeys-Dietz, Ehlers-Danlos)

  • Adult and Cardiovascular Genetics

  • Xia-Gibbs syndrome

  • Precision Medicine

  • Bioinformatics