Sandeep Krishna Agarwal, M.D., Ph.D.

Associate Professor and Section Chief
Baylor College of Medicine

Sandeep Krishna Agarwal, M.D., Ph.D. Photo

Position

Associate Professor and Section Chief
Medicine
Immunology, Allergy and Rheumatology
Baylor College of Medicine

Address

Baylor College of Medicine Medical Center, McNair Campus (Clinic)
7200 Cambridge St., 8th Floor, Suite 8A
Houston, Texas 77030
United States
(713) 798-3390
Google Maps

Certifications

  • Rheumatology
    American Board of Internal Medicine

Education

  • Clinical Fellowship at Brigham And Women's Hospital, Harvard Medical School
    Boston, Massachusetts United States

  • Postdoctoral Fellowship at Brigham And Women's Hospital, Harvard Medical School
    01/2007 - Boston, Massachusetts United States
  • MD from The University of Texas Health Science Center at Houston Medical School
    Houston, TX United States
  • PhD from The University of Texas Health Science Center at Houston Graduate School for Biomedical Sciences
    Houston, TX United States

  • Residency at Brigham and Women's Hospital/ Harvard Medical School
    Boston, Massachusetts United States

  • Internship at Brigham and Women's Hospital/Harvard Medical School
    Boston United States

  • BA from University Of Texas At Austin
    Austin, TX United States

Language

  • English

Gender

  • Male

Presentations

CPC - Dyspnea, Hallucinations, and Progressive Renal Dysfunction
Department of Medicine Grand Rounds
February 25, 2021

Contributor

CPC - Dyspnea, Hallucinations, and Progressive Renal Dysfunction
Department of Medicine Grand Rounds
February 25, 2021

Professional Statement

Dr. Sandeep Agarwal is a board certified rheumatologist and physician scientist with an independent research laboratory at Baylor College of Medicine. His clinical interests are largely in autoimmune and arthritic diseases (including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, systemic sclerosis/scleroderma, systemic lupus erythematosus, and vasculitis. Dr. Agarwal has a specific interest in autoimmune diseases that involve fibrosis of the skin, lungs and other internal organs, which is also the focus of his laboratory research. Dr. Agarwal’s laboratory is studying the mechanisms that underlie the development of autoimmune and fibrotic disease, including systemic sclerosis/scleroderma, rheumatoid arthritis, Sjogren’s syndrome and idiopathic pulmonary fibrosis. His laboratory is interested in the cells that mediate the fibrotic process, in particularly the interactions between fibroblasts and macrophages. His laboratory has identified increased expression of cadherin-11 in patients with scleroderma and idiopathic pulmonary fibrosis and demonstrated that cadherin-11 is a critical mediator of lung and skin fibrosis in mouse models. His laboratory has determined that cadherin-11 is an important regulator of epithelial-to-mesenchymal transition and also regulates macrophage behavior. His laboratory has continues to utilize mouse models, cellular and molecular immunology techniques and samples from patients to determine how cadherin-11 is regulating the development of fibrosis. He is currently working to translate these research findings into the care of patients with autoimmune fibrotic diseases. In addition to cadherin-11, his laboratory has identified a number of other candidate molecules, including osteopontin and STAT3, involved in autoimmunity and fibrosis. Ultimately, Dr. Agarwal and his laboratory seek to understand the complex cellular and molecular interactions that lead to tissue fibrosis with the goal of identifying novel therapeutic targets of patients with these diseases.

Professional Interests

  • Clinical : Diagnosis and management of autoimmune diseases including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, systemic sclerosis/scleroderma, systemic lupus erythematosus, Sjogren’s syndrome, polymyalgia rheumatica, vasculitis

  • Research :To understand the complex cellular and molecular interactions that lead to autoimmune diseases and tissue fibrosis with the goal of identifying novel therapeutic targets.

  • Systemic sclerosis

  • Autoimmune mediated lung fibrosis

Physician Specialties

  • Rheumatology

Professional Specialties

  • Rheumatology