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Recruiting

Start date: Jan. 3, 2022

Closure of GI defects after endoscopic resection decreases the rate of post resection bleeding. Traditionally, standard TTS clips have been used to close GI wall defects with some success. However, … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Dec. 8, 2021

Approximately 15-24 subjects will participate in the treatment part of this study. Maximum of 180 mL of blood (not exceeding 3ml/kg/day) is collected from patients to grow the T cells … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Dec. 7, 2021

Patients will first be asked to give blood to make the HER2 CAR T cells. These cells are grown and frozen for the patient. To get the HER2 antibody (and … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Dec. 1, 2021

Ventilatory suppression in children following opioid administration is of obvious concern, especially following routine surgical procedures (i.e. adenotonsillectomy). It is thought that patients with obstructive sleep apnea (OSA) have increased … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Nov. 4, 2021

Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism. With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Nov. 1, 2021

In this study the investigator will assess the effectiveness of a care coordination device (a supportive care device) called, Care4AD for reducing burden and stress of caregivers, enhancing patient adherence … Read More


Recruiting

Start date: Nov. 1, 2021

This study can be classified as a phase 1, single center, and drug-drug interaction (DDI) study. The within-subjects' experimental procedures will assess pharmacokinetic interactions between ethanol (EtOH) and PT150 (900 … Read More

BCM Role: Collaborator

Recruiting

Start date: Oct. 20, 2021

Immune thrombocytopenia (ITP) is the most common acquired immune cytopenia in childhood, affecting 4-6 in 100,000 children. The pathophysiology of ITP is highly complex and incompletely understood. Accepted mechanisms include … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Oct. 19, 2021

The purpose of this study is to help people with diabetes who develop neuropathic diabetic foot ulcers (DFUs). These ulcers, or sores, if left untreated can increase the chance of … Read More

BCM Role: Collaborator

Recruiting

Start date: Oct. 19, 2021

This project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the KCNQ-selective channel opener XEN1101 … Read More

BCM Role: Collaborator