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Completed

Start date: July 1, 1985

The Atherosclerosis Risk in Communities Study (ARIC), sponsored by the National Heart, Lung and Blood Institute (NHLBI), is a prospective epidemiologic study conducted in four U.S. communities. ARIC is designed … Read More

BCM Role: Collaborator

Completed

Start date: Sept. 1, 1986

BACKGROUND: Patients with classical hemophilia (hemophilia A) and Christmas disease (hemophilia B) were exposed to many hepatotropic viruses during the course of their therapy. Severe chronic hepatitis among these patients … Read More

BCM Role: Lead Sponsor

Unknown Status

Start date: April 1, 1989

OBJECTIVES: I. Determine whether intervention with a low-fat balanced diet will prolong the disease-free survival time in patients presenting with nonmelanomatous skin cancer and having a history of not more … Read More

BCM Role: Lead Sponsor

Available

Start date: June 1, 1989

The purpose of the protocol is to provide compassionate use of an efficacious drug, with few side effects, in an attempt to get rid of a variety of incapacitating dyskinesias … Read More


Completed

Start date: July 1, 1989

PROTOCOL OUTLINE: Participants are treated with subcutaneous leuprolide acetate followed by oral spironolactone. Each treatment is administered daily for 6 weeks, with a 6-week washout between drugs. Patients and controls … Read More

BCM Role: Collaborator

Completed

Start date: March 1, 1990

CMV retinitis is the most common intraocular infection in patients with AIDS and is estimated to affect 35 to 40 percent of patients with AIDS. Untreated CMV retinitis is a … Read More

BCM Role: Collaborator

Completed

Start date: June 1, 1990

Mafosfamide is given directly into the cerebrospinal fluid twice a week for six successive weeks. If after six weeks the disease has not shown any evidence of progression (tumor growth) … Read More

BCM Role: Lead Sponsor

Completed

Start date: Dec. 1, 1992

CMV retinitis is the most common intraocular infection in patients with AIDS and is estimated to affect 35 to 40 percent of patients with AIDS. Untreated CMV retinitis is a … Read More

BCM Role: Collaborator

Completed

Start date: Jan. 1, 1993

PROTOCOL OUTLINE: This is a randomized study. Patients are randomly assigned to a 6-month course of leuprolide versus ethinyl estradiol/norethindrone (Ovcon 35) versus leuprolide plus Ovcon 35. Leuprolide is administered … Read More

BCM Role: Collaborator

Completed

Start date: May 1, 1993

We will obtain blood from the donor and will first make a B cell line called a lymphoblastoid cell line or LCL by infecting the blood with a laboratory strain … Read More

BCM Role: Lead Sponsor