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Recruiting

Start date: Jan. 1, 2021

The goal of this project is to examine initial effectiveness of a brief (2 preoperative, 2 postoperative session) cognitive behaviorally-based telephone intervention compared to standard care on postoperative outcomes for … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Nov. 23, 2020

1. OBJECTIVES 1.1 Primary Objectives 1.1.1 To assess the effect of a 7-day course of oral cyclosporine Neoral on clinical outcome using the World Health Organization (WHO) COVID Ordinal Clinical … Read More


Recruiting

Start date: Nov. 4, 2020

The first part of this study is to identify the maximum tolerated dose (MTD) of allogeneic SARS-CoV2-specific T cells (SARS-CoVSTs) for patients with COVID19 with high risk of progression to … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Oct. 1, 2020

The incidence of moderate to severe congenital heart disease (CHD) in the United States is estimated to be 6 per 1000 live-born full term infants. Recent advances in pediatric cardiology, … Read More

BCM Role: Collaborator

Recruiting

Start date: Sept. 16, 2020

Earlier, healthy donors gave blood for us to make CD30.CAR-EBVST cells in the laboratory. These cells were grown and frozen and the investigators will select the donor which the investigators … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Sept. 7, 2020

Pediatric urologic surgery is generally accompanied by use of a caudal or penile block for analgesia. A caudal block is performed by injecting local anesthetic in the low epidural space … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Sept. 1, 2020

An initial single-dose PK study will be carried out. Forty-two children (n=21 per dose) will be randomized to receive approximately 10.9 mg·kg-1·d-1 of PMO or to receive approximately 18.2 mg·kg-1·d-1 … Read More

BCM Role: Lead Sponsor

Recruiting

Start date: Aug. 25, 2020

Approximately 5,000 children die from septic shock each year in the United States (US); thousands more die worldwide. Most children admitted with sepsis receive initial resuscitation in an emergency department … Read More

BCM Role: Collaborator

Recruiting

Start date: Aug. 6, 2020

The ESTHI Trial is a multi-center randomized controlled trial (RCT) comparing endoscopic third ventriculostomy with choroid plexus cauterization (ETV+CPC) and shunt in infants with hydrocephalus. The study will leverage the … Read More

BCM Role: Collaborator

Recruiting

Start date: Aug. 3, 2020

The primary objective of this phase 1, first in man trial is to determine the safety, toxicity, and feasibility of delivering autologous dendritic cells (DCs) loaded with pancreatic adenocarcinoma lysate … Read More

BCM Role: Lead Sponsor